Early Bilateral Gonadoblastoma in a Patient with Mixed Gonadal Dysgenesis (Karyotype 45,X/46,XY): Case Report and Review of Literature
نویسندگان
چکیده
Background: Mixed gonadal dysgenesis is a rare congenital and challenging condition, characterized mainly by 45,X/46,XY karyotype mosaicism, asymmetrical development various internal external genital anatomy. Because of frequent disorder higher risk germ cell neoplasia, management these patients complex requires multidisciplinary approach.Case: We present mixed patient diagnosed with gonadoblastoma in both gonads after bilateral gonadectomy at 1 year age.Conclusions: high for malignant transformation, streak-like gonad biopsy orchidopexy or dysgenetic testicle recommended an early age.
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ژورنال
عنوان ژورنال: Acta medica Lituanica
سال: 2022
ISSN: ['1392-0138', '2029-4174']
DOI: https://doi.org/10.15388/amed.2022.29.2.5